botiss reaches 
for the stars

A revolutionary leap forward

In a revolutionary leap forward in the world of regenerative dentistry, botiss biomaterials GmbH has reached for the stars in its inspiration for developing the next generation of dental materials. Released by stars during supernova explosions as well as naturally occurring on Earth, magnesium is a material with an ideal mix of properties suited for tissue regeneration. With the first ever dental magnesium implants to receive CE approval, botiss has brought a break-through technology into the field of dentistry. The launch of the NOVAMag® regeneration system provides an option to dentists seeking a biomaterial that is mechanically strong yet completely bioresorbable, being replaced over time with natural bone. 

Led By Science

Instigated by one of the leading experts in the field, Prof. Dr. Frank Witte, and supported by strong collaborations with scientific institutes, such as the Charité Universitätsmedizin Berlin, the Fraunhofer Gesellschaft (IFAM) in Dresden, and Helmholtz-Zentrum in Geestacht, as well as a network of other leading global interdisciplinary scientists and dental professionals, the NOVAMag® regeneration system has undergone extensive testing. Numerous biomechanical, in-vitro and in-vivo studies as well as biocompatibility and toxicological studies have been performed that have established the safety and efficacy of these devices. 

A whole new 
regeneration system

The NOVAMag® regeneration system comprises of the NOVAMag® membrane and NOVAMag® fixation screw, intended to be used for augmentation procedures in the alveolar ridge. The NOVAMag® membrane is a magnesium membrane and the NOVAMag® fixation screw is a set of magnesium fixation screws in different sizes that can be used for the fixation of barrier membranes and bone blocks. By its unique features, the NOVAMag® product line offers a minimally invasive approach for the patient as the implants do not need to be removed in a second surgery. This also benefits dental professionals by cutting down on chair time.

Starting from Q2 2021, selected clinicians will have the unique opportunity to participate in national and international PMCF activities. All currently available slots are already taken. But drop us a note in case you are interested in participating in the next turns. 

The NOVAMag® system is not yet commercially available.


The NOVAMag® membrane is a completely resorbable, biodegradable metal membrane intended to be used in stomatology and maxillofacial surgery, implantology, periodontology and oral surgery to support guided tissue and bone regeneration, for covering implants and for periodontal tissue regeneration.

The NOVAMag® membrane is produced out of pure magnesium and has a shiny metallic surface. It is of synthetic origin removing the risk of disease transmission.

The NOVAMag® membrane has a good biocompatibility and mechanical strength and is usually completely resorbed within a few months after implantation. Therefore, there is no need to remove the membrane in a second surgical intervention.


The NOVAMag® fixation screw is composed of a completely resorbable, biodegradable, magnesium metal alloy and is available in various sizes for use in stomatology and maxillofacial surgery, implantology, periodontology and oral surgery, to be used for the fixation of barrier membranes and/or bone grafts or bone filling material, in the support of guided tissue and bone regeneration.

The biodegradable magnesium alloy used for the fixation screw as well as its surface treatment is designed to slow down resorption during the initial wound healing phase, thereby providing a sufficient stabilization of the barrier membrane or bone graft. It is of synthetic origin removing the risk of disease transmission.

NOVAMag® fixation screws are usually resorbed approximately one year after implantation. Therefore, there is no need to remove the screws in a second surgical intervention.


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botiss biomaterials GmbH
Janika Vogel
Hauptstraße 28
15806 Zossen / Germany
Phone: +49 33769 8841992

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